Mary Glenn Perine (1822-1896) was the daughter of Mary Glenn, the daughter of Judge Elias Glenn, and David Maulden Perine, the son of Maulden and Hephzibah Perine. She was one of eight children: Ann Carson (1819-1919); Susan Buchanan (1820-1899); Mary Glenn (1822-1896); William Buchanan (1823-1863); Rebecca Young (1825-1879); David Maulden, Jr (1827-1847); Elias Glenn (1829-1922); and Thomas Harwood (1830-1861).
Mary Glen Perine's father was the Registrar of Wills in Baltimore City and county from 1811 to 1851. He was the owner of the Homeland estate north of Baltimore, which property was in his family from 1799, when his widowed mother married William Buchanan (he had purchased the estate). Perine built two mansions (the first one burned down), some thirty farm buildings and tenant quarters, which stood on the land until 1924. Anna McNeill Whistler was the godmother of Mary's youngest brother Thomas Harwood Perine.
In 1859 Mary met Whistler at the Hadens' house in London. She found him looking very well but thought that he was longing to get back to Paris. Visiting her not long after, Whistler showed her some of his etchings which she greatly admired (). During a trip abroad in 1868 Mary once again visited Whistler in London, noting in her diary in some detail the oriental furnishings of his parlour at Lindsay Row, Chelsea ().
Andrews, Mathew Page, Tercentenary History of Maryland, Chicago, 1925, vol. 4, pp. 67-69.